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Evolution from Proto-Life to Metabolic Networks: Difference between revisions

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** Yes, I though it might be interesting to run simulations without fitness and selection, just based on the rules of evolution and see what comes out -- [http://www.santafe.edu/events/workshops/index.php/Amelie_Veron Amelie]
** Yes, I though it might be interesting to run simulations without fitness and selection, just based on the rules of evolution and see what comes out -- [http://www.santafe.edu/events/workshops/index.php/Amelie_Veron Amelie]
*** What to do about the explosion of possibilities? [[http://www.santafe.edu/events/workshops/index.php/Tim_Johann Tim]]
*** What to do about the explosion of possibilities? [[http://www.santafe.edu/events/workshops/index.php/Tim_Johann Tim]]
* How can we get increasing complexity of metabolites?
* How can we get increasing structural complexity of metabolites?




== Readings ==
== Readings ==
* nearly anything by Stuart Kauffman (I just borrowed 'The Origins of Order').
* nearly anything by Stuart Kauffman (I just borrowed 'The Origins of Order').

Revision as of 03:45, 7 June 2007

CSSS Santa Fe 2007

First meeting scheduled for Thu, Jun 7, 10:15am after the lecture.

People

(Just sign up yourself, if interested, or, whom I've just forgotten)

  • Kathryn Cooper
  • Amelie Veron
  • Wenyun Zuo
  • Christian Darabos
  • Tim Johann
  • Vikas Shah
  • Joshua L. Payne

Idea

Given the concept of the Metabolism First Hypothesis, how did early simple and essentially random reaction networks evolve into ones that exhibit characteristics of scale-free and small-world networks? What physically meaningful rules may we find that can lead to this?


Things to consider

  • No predefined goal! Besides evolvability.
  • How to define fitness? Or, how to define selection without a known fitness function?
    • Yes, I though it might be interesting to run simulations without fitness and selection, just based on the rules of evolution and see what comes out -- Amelie
      • What to do about the explosion of possibilities? [Tim]
  • How can we get increasing structural complexity of metabolites?


Readings

  • nearly anything by Stuart Kauffman (I just borrowed 'The Origins of Order').