Learning & the aging brain: Difference between revisions
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{{CSSS 2007 Santa Fe}} | {{CSSS 2007 Santa Fe}} | ||
'''Next meeting: Monday, June 11, 7PM: should present short blurb on exploratory topics''' | |||
==Concept== | ==Concept== | ||
We can mimic the effect of aging on the human brain by deliberately corrupting neural network models of human learning (e.g. random deletion of nodes/synapses). | We can mimic the effect of aging on the human brain by deliberately corrupting neural network models of human learning (e.g. random deletion of nodes/synapses). | ||
Possible directions include: exploring compensatory mechanisms for neuronal loss (related to self-healing networks?), modeling specific age-related diseases - e.g. Alzheimer's, Parkinson's (chaos & tremors?). | Possible directions include: exploring compensatory mechanisms for neuronal loss (related to self-healing networks?), modeling specific age-related diseases - e.g. Alzheimer's, Parkinson's (chaos & tremors?). | ||
Please feel free to add questions, theories, suggestions. | Please feel free to add questions, theories, suggestions. | ||
==Who's interested== | ==Who's interested== | ||
Kristen Fortney | *Kristen Fortney | ||
*Gregor Obernosterer | |||
Gregor Obernosterer | *Amitabh Trehan | ||
*Vikas Shah | |||
Amitabh Trehan | *Biljana Petreska | ||
*Amelie Veron | |||
Vikas Shah | *Wenyun Zuo | ||
*Saleha Habibullah | |||
Biljana Petreska | *Yossi Yovel | ||
*jd | |||
Amelie Veron | *Natasha Qaisar | ||
Wenyun Zuo | |||
Saleha Habibullah | |||
Yossi Yovel | |||
jd | |||
Natasha Qaisar | |||
==Questions to answer== | ==Questions to answer== | ||
Revision as of 17:13, 6 June 2007
| CSSS Santa Fe 2007 |
Next meeting: Monday, June 11, 7PM: should present short blurb on exploratory topics
Concept
We can mimic the effect of aging on the human brain by deliberately corrupting neural network models of human learning (e.g. random deletion of nodes/synapses).
Possible directions include: exploring compensatory mechanisms for neuronal loss (related to self-healing networks?), modeling specific age-related diseases - e.g. Alzheimer's, Parkinson's (chaos & tremors?).
Please feel free to add questions, theories, suggestions.
Who's interested
- Kristen Fortney
- Gregor Obernosterer
- Amitabh Trehan
- Vikas Shah
- Biljana Petreska
- Amelie Veron
- Wenyun Zuo
- Saleha Habibullah
- Yossi Yovel
- jd
- Natasha Qaisar
Questions to answer
What sorts of age defects should be incorporated into the network?
What type of neural net should be used as a model? (backprop/attractor/etc)
Background reading
Integrative neurocomputational perspectives on cognitive aging, neuromodulation, and representation. - Li and Sikstrom http://www.lucs.lu.se/People/Sverker.Sikstrom/NBR-Li-Sikstrom.pdf
Neuroengineering models of brain disease. - Finkel
http://www.mssm.edu/cnic/pdfs/FinkelNeuroengineering.pdf
Patterns of functional damage in neural network models of associative memory
http://www.cs.tau.ac.il/~ruppin/spat.pdf
What is physiologic complexity and how does it change with aging and disease? - Goldberger, Peng, Lipsitz http://reylab.bidmc.harvard.edu/heartsongs/neurobiology-of-aging-2002-v23-23.pdf
Exploratory committees
General note: all should look at best neural network approach to their problem
- Demyelination: Biljana & Yossi
- Process to model these systems, time-delay in neural networks
- Biology of MS
- Normal aging: Kristin & Vikas & Amitabh
- Biological underpinning, general patterns of damage
- Parkinson's disease: jd & Kristin
- Alzheimer's disease: Gregor & Natasha & Vikas
- Boolean networks and self-healing: Amelie & Amitabh & Wenyun
- Social implications of aging: Saleha & Amelie