Integrating Evolutionary Theory into Cancer Biology - Background Papers

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Crespi, B. and K. Summers 2005. Evolutionary biology of cancer. Trends in Ecology & Evolution 20(10): 545-552.

Gatenby, R. A. and T. L. Vincent 2003. An evolutionary model of carcinogenesis. Cancer Research 63(19): 6212-6220.
Hanahan, D. and R. A. Weinberg (2000). The hallmarks of cancer. Cell 100(1): 57-70.

Maley, C. C. and B. J. Reid 2005. Natural selection in neoplastic progression of Barrett's esophagus. Seminars in Cancer Biology 15(6): 474-483.

Merlo, L.M.F., Pepper, J.W., Reid, B.J., and Maley, C.C. 2006. Cancer as an evolutionary and ecological process. Nature Reviews Cancer. 6: 924-935.

Spencer, S. L., R. A. Gerety, K.J. Pienta, and S. Forrest. 2006. Modeling somatic evolution in tumorigenesis. Plos Computational Biology 2: 939-947.

Vincent, T. L. and R. A. Gatenby (2008). "An evolutionary model for initiation, promotion, and progression in carcinogenesis. International Journal of Oncology 32(4): 729-737.