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Revision as of 04:59, 12 June 2008 by RobMills
This is the working space for our project. Everything written is a work in progress.
- Evolution of modularity in a host-pathogen system
- Modularity: a pathogen's answer to host interactions
- more here
- Does modularity in pathogen genes responsible for an interaction with a host increase its ability to adapt to a host?
- Is modularity in the host required for pathogen modularity to arise/emerge?
- additional ones here
Discrete or continuous?
- Pros for discrete: easier to run iterated simulations; possible to run experiments on explicit graph structures
- Pros for continuous: mathematical derivations cleaner
I'm quite sure that there is some overloading here; but these are the types of modularity that have come up in our discussions:
- Modularity for reassortment (Molly)
- Modularity for independence (Molly) (I call this 'functional decomposition' - Rob)
- Repeated modularity: eg where a body segment occurs many times in an organism (Rob)
- Modularity for robustness to antagonistic pleiotrophy (Molly)
- Epitope : the phenotype of a pathogen that interacts with a host
- only need to consider a portion of the host's genome since the pathogen only targets a specialised portion of that genome.