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I received a BSc in Computer Science and an MSc degree in Molecular Biology from the [http://www.univie.ac.at University of Vienna], Austria. In 2003 I joined the International NRW Graduate School for Bioinformatics and Genome Research in Bielefeld, Germany as a Research Assistant where I worked with Marc Rehmsmeier mainly on the prediction of microRNAs (miRNAs). In 2005 I moved back to Vienna and started my PhD at the [http://www.imba.oeaw.ac.at Institute of Molecular Biotechnology], IMBA under the supervision of Javier Martinez. Still I am mainly interested in predicting miRNA target genes and understanding their biological function. Together with Gerhard Schratt from the University of Heidelberg I could identify a brain specific miRNA that seems to regulate the size of dendritic spines. In the future, it will be interesting to learn to understand the mechansim the miRNA plays in regulating the size of synapses and if this has any effect on learning and memory. Furthermore, I am working with Ivo Hofacker from the [http://www.tbi.univie.ac.at Institute of Theoretical Biochemistry], TBI, Vienna where I am trying to incorporate how RNA secondary structure around target sites affect miRNA and siRNA binding.
 
siRNA design tool [http://rna.tbi.univie.ac.at/cgi-bin/RNAxs RNA''xs'']  
 
 
COLLABORATORS:
 
[http://www.wi.mit.edu/research/fellows/brummelkamp.html Thijn Brummelkamp]
 
[http://www.imba.oeaw.ac.at/research/javier-martinez Javier Martinez]
 
[http://www.izn.uni-heidelberg.de/index.php?option=com_content&task=view&id=126&Itemid=228 Gerhard Schratt]
 
[http://www.tbi.univie.ac.at/~ivo Ivo Hofacker]


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  Gregor Obernosterer                     
  Gregor Obernosterer                     
  Institute of Molecular Biotechnology
  Massachusetts Institute of Technology
  of the Austrian Academy of Sciences
  Whitehead Institute for Biomedical Research
  Dr. Bohr-Gasse 3
  9 Cambridge Center
  1030 Vienna, Austria
  MA 02142 Cambridge
  Tel.: +43 1 79044 4858
  Tel.: +1 617 324 5869
Fax.: +43 1 79044 110
  eMail: gregor AT wi.mit.edu
  eMail: gregor AT tbi.univie.ac.at
  W3: http://www.wi.mit.edu
  http://www.imba.oeaw.ac.at

Latest revision as of 11:02, 19 March 2011


siRNA design tool RNAxs


COLLABORATORS:

Thijn Brummelkamp

Javier Martinez

Gerhard Schratt

Ivo Hofacker



Gregor Obernosterer                     
Massachusetts Institute of Technology
Whitehead Institute for Biomedical Research
9 Cambridge Center
MA 02142 Cambridge
Tel.: +1 617 324 5869
eMail: gregor AT wi.mit.edu
W3: http://www.wi.mit.edu